It is a local vasodilator, which promotes an improvement of capillary microcirculation, and also acts prolonging cell multiplication and, thus, the hair growth phase (anagen phase). By regulating the growth cycle of the hair follicle, the process of hair miniaturisation in androgenic alopecia can be reversed. Its action occurs only on follicles subjected to miniaturisation, but not on fully miniaturised follicles. It has no action on normal follicles as well. Briefly, Minoxidil prolongs hair growth and increases the size of the hair follicle, causing hair loss in the telogen phase and inducing the formation of new hair in the anagen phase.
- It begins 15 days after the hair transplant.
- It has the effect of reducing Shock Loss (Post-surgical effluvium).
- It accelerates the growth of transplanted hairs.
It is believed that its action mechanism is the opening of potassium and nitric oxide channels, thus improving vasodilation.
How to use it?
- In the market, the most common concentrations are 2% and 5%.
- It is used topically (lotion).
- Apply 1ml twice a day or 2ml at night with a dropper.
Minoxidil lotion should be applied to the scalp with dry hair. To obtain good results it must be used regularly, with noticeable effects from the 4th-6th month.
Generally, Minoxidil is well tolerated when used topically (scalp application) with few side effects that tend to decrease with continued treatment.
The most common side effect is:
- Allergic reaction caused by contact dermatitis, which is generally due to an irritant action provoked by the use of propylene glycol as an alcoholic vehicle. Nowadays you can buy Minoxidil lotions without propylene glycol, which reduce the risk of allergic reactions to this component.
- Hypertrichosis in unwanted areas touched by Minoxidil.
- Rarely headaches.
- Despite the possible adverse reactions described above, as a rule it is well tolerated by most users when applied correctly.
- Between the 3rd and 6th week after starting treatment with Minoxidil, you may notice a phenomenon of DreadShed, which is temporary hair loss.
- It is an accelerated loss of weak and miniaturised hair to make way for stronger and healthier hair.
- This phenomenon is positive, evidencing that the current is favourably acting medication in the body.
- Minoxidil is usually administered in conjunction with other medications to promote hair growth, this joint administration being much more effective for hair growth.
- This medicine should not be used by pregnant or breastfeeding women, and should be avoided or used with caution by hypotensive patients (with low blood pressure) or by those with serious heart problems.