Diffuse alopecia without pattern (DUPA) is a type of androgenetic alopecia with no defined fall pattern. This type of alopecia manifests capillary loss in all areas of the scalp, both in the upper area, as in the back and on the sides so it lacks a stable and permanent donor area.
In the hair loss process, the hairline is maintained, but there is a decrease in overall density throughout the head.
It is believed that DUPA is a genetic process. It can occur at any age and usually occurs more in women than in men, they are much more likely to suffer DUPA than men. In men it affects less than the DPA but it does it in a rather accelerated way.
The main symptom is the rapid and continuous loss of hair from all areas of the head.
Diagnosing DUPA diffuse alopecia correctly is of vital importance. Patients who suffer from it should not undergo a hair transplant since their donor area is not stable and presents capillary loss so, if a hair transplant is performed, it would fall again as those hair are also affected by the DUPA .
The videodermoscopic examination is useful to diagnose diffuse alopecia DUPA.
DUPA can be controlled by taking medications such as Finasteride and Minoxidil. Finasteride prevents 5-alpha reductase from metabolizing testosterone in DHT and Minoxidil thickens the hair and lengthens the anagen phase of the follicle.